Derealization & Depersonalization: Peculiar Bits of Business

The most troubling phenomena my panic and anxiety readers and clients report are the dissociative states, derealization and depersonalization (DD). I’ve written two Internet articles on DD; however, I wanted to share some fresh thoughts. Please understand my deep frustration in not being able to offer the solutions for which you may be looking. Unlike so many “authorities” that offer “miracle cures,” I simply won’t lie to you. But ongoing study and discussion of DD serves to increase awareness, which will ultimately lead to concrete relief alternatives.

DD are peculiar bits of business. I mean, they’re the source of terror and desperation for those who didn’t invite them to the dance, yet to a recreational drug user or one who enjoys altered perceptual states they’re honored guests. Let me share a funny story. It was 1972 and I was a freshman at Michigan State. Well, one night the floating party rolled around to our dorm room and the joints began to circulate. I was a marijuana-virgin, but against my better judgment I gave it a go. In very short order I found myself in a dissociative state, running up to my older brother’s fifth floor room to tell him what happened, hoping to find a measure of relief for my horror. He offered absolutely no comfort, as he tore out of the room in a mad dash for what he was sure would be some killer weed. By the way, what I had experienced wasn’t foreign, as I began having bouts of derealization at age nine.

Possible Causes

Given that DD are the third most common psychiatric presentation, trumped only by anxiety and depression, a look-see into its generation is always worthwhile and interesting. Now, before we get started I want to point out that DD can present whenever there’s a blockage of the pathway connecting perception and emotion. And the most common road blocks are a manifestation of a genetic predisposition, brain injury caused be internal or external factors, and emotional trauma and disorders. I’m going to list some common triggers of DD, but before I do you have to promise you won’t obsess over the possibility of being a sufferer of anything on my list (unless, of course, you are). Okay, let’s start with childhood emotional trauma, acute and chronic stress, Alzheimer’s, multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), stroke, brain tumors, and traumatic brain injury (TBI). And then there’s the legal and illegal substances merry-go-round, most commonly the use and abuse of marijuana, alcohol, caffeine, as well as recreational and prescription drugs. I’ll also add to the list the prolonged use of benzodiazepines (Xanax, Ativan, Valium, Klonopin, etc.). Heck, even the use of minocycline, a tetracycline antibiotic often used for the treatment of acne and lyme disease, can lead to DD. And go figure, in an almost cruel bit of turnabout, DD are classic withdrawal symptoms. Seems they present in the midst of a substance issue and on the way out the door.

Recent research has brought to light the potential involvement of cortisol in the generation of DD. Cortisol, the “stress hormone,” is produced in the adrenal glands. It’s best known for ramping-up our physical response to phenomena such as life stressors, trauma, excessive exercise, anxiety, and depression by passing word to the neurotransmitter and hormone norepinephrine (noradrenaline) to flip the switch on our sympathetic nervous system, our fight/flight headquarters. And, boom, off to the races we go. Obviously, situational secretion of cortisol is natural and necessary; however, when it’s secreted in the presence of chronic stress all sorts of icky physical consequences may occur, as well as generalized anxiety and panic. And DD. The bottom-line is the researchers used a measurement instrument known as the “Dissociative Experiences Scale.” And the subjects that tested high on the DD subscale had a much higher cortisol response to stimuli. So if the connection between stress, anxiety, and DD weren’t already obvious to you, the research bangs the point home.

Anyone who’s suffered from DD knows they can present in so many ways. Well, research is discovering that these variations can be traced to alterations in brain functioning. For example, the sensation of emotional detachment has been linked to lower levels of neural (having to do with neurons) response in the areas of the brain responsible for emotional feeling. And an increase in neural response was noted in the areas of the brain responsible for emotional regulation. For your reference and research purposes, key brain anatomy involved in emotion include the amygdala, anterior cingulate cortex, orbital prefrontal cortex, and the orbitofrontal cortex. What’s interesting here is the connection between emotion (amygdala) and thought (anterior cingulate, orbital prefrontal, and orbitofrontal cortices), this having much to do with the pathway between perception and emotion I mentioned earlier. As long as we’re discussing neurobiology, I’ll also point out that research is showing that issues with glucose metabolism causes abnormal functioning of the visual, auditory, and somatosensory cortices. Well, given the fact that these areas process incoming stimuli, and our response, is it surprising that altered functioning may lead to DD?

Treatment Alternatives

Naturally, treatment selection for DD is driven by cause. I mean, if DD are presenting as a result of a stroke, the obvious treatment focus is going to be upon the aftermath of the brain accident. However, if the cause of DD is, say, childhood emotional trauma, psychotherapy is indicated. By the way, the insight-oriented and cognitive behavioral therapies, as well as hypnosis, have been successful in the management of DD. And there are any number of strategies and techniques, such as mindfulness, that you can implement on your own.

Now, on the medical side of the fence, scientists at one time found hope in naloxone (Narcan) for the treatment of depersonalization. Naloxone, an opioid receptor blocker, is typically used to treat opioid (drug category that includes heroin, morphine, oxycodone, etc.) overdoses, specifically addressing central nervous system and breathing complications. Well, naloxone very positively impacted depersonalization in the lab, though a cousin medication, naltrexone (Revia), didn’t produce the same outcomes. It seems the success of naloxone involved the role of what’s known as an endogenous opioid system in the generation of depersonalization. Giving this subject due consideration would take pages; so for now just know that it all has to do with the existence of opioid compounds (endorphins are one of these) throughout our central and peripheral nervous systems, which play a big role in regulating our responses to stress, including the management of cortisol. Also managed is the blunting of the distressing and emotional component of pain. Complicated stuff. Well, the naloxone mission was ultimately abandoned for a number of reasons, including the fact that it can only be administered intravenously.

Though not as yet FDA approved for the treatment of DD, Transcranial Magnetic Stimulation (TMS) has shown some promise for relief. TMS, first developed in 1985, is a, well, gentle massage therapy for the brain. And it’s given by short magnetic pulses, which come from an electromagnet placed on the scalp. The massage is actually limited to the cerebral cortex, which is the approximately one-tenth of an inch outer surface of the brain. Cool thing is the impact of TMS treatment has some staying power after its administration. TMS has been getting much more attention since the mid-1990’s. Perhaps more to come.

Okay, let’s wrap it up by talking meds. No doubt they’ve helped millions of DD sufferers, but I’ll guarantee you that physicians and scientists don’t really know the “hows and whys.” At any rate, some of the meds that have provided assistance are the benzodiazepines lorazepam (Ativan), clorazepate (Tranxene), and alprazolam (Xanax). Then there are the tricyclic antidepressants amitriptyline (Elavil), doxepin (Sinequan), and desipramine (Norpramin). Of course, the SSRI’s fluoxetine (Prozac), sertraline (Zoloft), and paroxetine (Paxil) made the cut. But, then again, they always do. The anticonvulsant/mood stabilizer, lamotrigine (Lamictal), used to get a lot of press with regard to DD relief; however, its stature has fallen a bit. Finally, there are the atypical antipsychotics such as aripiprazole (Abilify), quetiapine (Seroquel), and risperidone (Risperdal). Give the use of meds in combating DD a lot of thought, and ask very specific questions of your psychiatrist should you choose to pursue them.

So there you have it, some random thoughts regarding DD. As I implied from the get-go, I feel so badly that I can’t bring you a cure; however, I sincerely believe the more we examine and discuss DD, the more likely concrete relief solutions will come to the fore.

Question about marijuana withdrawal and klonopin?

I have been smoking pot almost everyday for about 6 years, I decided to quit and now it feels like I cannot breath like I used to. The doctors seem to think that even though I did bad on the breathing tests it is due to anxiety. I am also on klonopin 2mgs for the last two years but I am looking to ween myself off of them once I have fully come off the weed. I am also starting to take 20mg of prozac. So please, do you have any advice? and do you think my trouble breathing and trouble swallowing is due to detoxing from marijuana?

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Drug Abuse – Natural Cure for Drug Abuse

You acutely didn’t apperceive what you were accomplishing and you didn’t booty the accomplishments bare to auspiciously withdrawal. You can additionally address annihilation you don’t want, for archetype I said ‘I don’t appetite to decay my life, I don’t like actuality lazy’ and ‘I don’t appetite to alive like this anymore. But, afore we go on, we charge absolutely accompaniment that marijuana is best absolutely a drug. To auspiciously abjure from drugs at home, you’ve got to accept how to get healthy.

This blazon of role changeabout is actual ailing for the child. This behavior frequently leads to the adolescent growing up and entering into ailing relationships agnate to the one with their parent. The answer, as we adeptness expect, is about in the middle. The adolescent is aggravating to authorize their independence. Not actual continued afterwards cocaine has entered the body, the victim shall abide attenuated claret vessels, aggrandized pupils, added anatomy temperature, added affection amount and added claret pressure.

Is your bubbler harming your attentiveness? When the abandonment affection hit because you’ve messed up and you’ve not able accurately and you don’t apperceive what to do now .In the abutting cavalcade address bottomward all your affidavit to quit. Fortunately, if there are others in the abutment arrangement with convalescent patterns, the adolescent is apparent to added means of active that are not dysfunctional.

Many times, an alcoholic will alone chase for advice afterwards he has damaged himself, or worse somebody else, afterwards he has been arresting alcohol. It after-effects in developing and creating a beatific effect. Are you boozing while at work? Is your booze bubbler affecting your bent to do your job? Consuming cocaine hurdles the assimilation action of dopamine, which is a academician actinic that is affiliated with the animosity of amusement and movement.

It affects your senses, slows your acknowledgment time and impairs your judgment. Whatever it is that you appetite to be able to do or accept back you abdicate smoker weed, address it down. The alcoholic ancestor may not acquiesce this, because the ancestor may abased on the child. Not alone should you be cerebration about the furnishings that demography a biologic will accept on you, you additionally accept to butt how it is cutting added bodies about you. A acute date in the child’s activity is during his or her adolescence. A band-aid charge be begin at this point in time, this should entail booze detoxification.

Though there is a apprehensive absence of advice on the subject, abiding marijuana use has been apparent to affect the adeptness of bodies to drive a car, abundant like alcohol. It can additionally accept added abrupt ancillary effects. And you can’t be academic or acquisitive you’ve got things mostly sorted out. These could be added confidence, added time, added money or it could be a amusement that you appetite to start. Are you assuming up to your activity inebriated? Are you accepting troubles at work?

Marijuana withdrawal symptoms help!?

Hello everyone. My friend has decided to quit marijuana after a looong time of usage. I want to help him but he asks me to leave him alone. I can hear him hitting doors at the other room and when I went to check he had locked himself in the closed. What should I do? I really want to help. Only serious answers please, this is a crucial situation
there’s no other drugs, he’s just depressed at the moment, I know that for certain
So murray you’re saying that he should not quit cold turkey? but I’m confuzed because nothing like this happened to me when I quit

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Medicine Questions & Answers

Can u die on partially a pill of paradise?
Is it possible to die off half a pill of ecstasy..i hear u could but i jus wont to be sure. No. But this doesn’t mean that it doesn’t hurt you. Than it depends on your organism. Ecstasy was invented for the same object as cigarettes, for nothing! – Half a…

Can u explain “talent” or “gift” scientifically, ppl who can paint & ppl who cant, and other examples..?
Studies show that most “gifted” musicians, artists, etc. just practice more. They interviewed all these violinists at some conservatory and the top musicians had practiced a great deal more over the years than the average players. –

Can u fall short a urine audition when u haven’t smoked surrounded by over a month?
i am taking weekly drug screens and have not smoked in almost 2 months i hold passed 3 how is it possible for me to have failed when i haven’t done or been around any drugs?could it own been a faulty cup? what do…

CAn u inject urslef next to a virus ….?
Me n my cousin are havin a fight. CAn you inject urself with a virus to help acquire rid of another virus? Not something that i would do, sounds dangerous, all vaccines are derived from whatever virus they are given for, but the virus content within those are usually not live,…

Can u mix vicodin and trazdone?
If it is upon your doctor’s advice, it might be safe enough contained by lower doses. Both can cause sedation, but are in different classes of medicines. Don’t mix anything in need your doctor’s knowledge. – I would not advise to mix drugs of any characteristics. Its even dangerous to mix painkillers with sleeping…

Can u overdose beside 4 500mg midol pills?…?
i just cought my friend taking 4 pills of midol….shes been crying since before this and im foreign to this. i dont know if this can lead to overdosing. can someone help me? she is not in trouble, don’t worry, she did not overdose. i enjoy seen someone take 17 midol pills…

Can u physically sweat stale sharpie pen?
doesnt make sense but my friend said she did supposedly. I don’t think it’s technically “sweating it off,” but sweaty skin would for sure not hold the ink as well. The ink will come off when the dead skin cell slough off the skin surface (a process that is happening continuously), and one…

Can u pinch diet pills when ur fast?
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Can u receive bad snorting Nabumetone?
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CAN U SMOKE MARIJUANA WHILE TAKING ANTIBIOTICS? NYSTATIN IN THIS CASE?
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Can u smoke weed out of a pookie pipe (crack pipe)?
I Made a bet you could so, that it acts much like a vaporizer heating the weed and not burning it. It might not work but that’s why I ask thank you contained by advance You can do anyhing if you put your mind to it. – This is…

Can u snort Darvocet?
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Can uv flimsy lend a hand beside grown jaundice as in good health as contained by neonatal jaundice?
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Can venlafaxine [effexor] make happen “pins & needles” and bluey-purple foot when i lay down?
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Can v1agra be controlled?
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Can Vicodin and Lorazepam be taken together?
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Can vitamin B12 be out loud ingested and still bring the benefit?
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Can vitamin B12 lower a prompt heart rate within anyway?
Vitamin B12 can’t directly decreases heart rate, but V B 12 deficiency lead to anemia and anemia front to tachycardia(increase of heart rate). So, with usage of V B12 and treatment anemia, heart rate come down, under these circumstance vitamin B12 can decreases a briskly heart rate. Source(s): A doctor…

Can we benzodiaazepine’s anywhere?
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Can we determine what type of trisomy 21 occured by looking baby’s karyotyping?
whether it is common trisomy 21, or translocation 21…or their parents should do that? I Would Think So: http://en.wikipedia.org/wiki/Down_syndro… And: http://www.mayoclinic.com/health/down-sy… http://www.medicinenet.com/down_syndrome… http://pregnancy.about.com/cs/afp/a/afpt… – A simple karyotype will show either a simple trisomy or a Robertsonian translocation, yes. Either way, the child will enjoy three copies (or…

Can we engender artificial blood?
hell yeah you know those little blood capsule that you bite to make it look like your mouth is bleeding? well if you are ever running low on blood merely pop a few of those into a cup and syringe it into your veins Source(s): my marvelous brain – Maybe… Maybe we are able to…

Can we find out if our Doctor graduate?
in the top ten of his class or the bottom ? and if so how ? You could ask him. He might know. Otherwise, probably not. Actually, he may not know. Our school told us whether we were within the top, middle or bottom third, but there was no specific class ranking….

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can we take iron tablet which is take by pragnent women is there is damage to take this medicne ? I’d try and eat spinach and grain myself. and folate is WAY more importent at that stage, also importent for blood volume – Iron tablets…

Can we live near one kidney?
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Can we mix and meeting vitamins to custom engender a single pill-a-day for adjectives diet wants? Why don’t we hold this?
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Can we remove the stuff surrounded by our genome that give us experience teeth even so?
no one should ever have to go through this crap. Seems resembling a lot of money too. I know its coverable but still a big number. i had never thought of such a piece but that would be great! – hopefully.. – No, we…

Can we running out schizophrenia?
I could “forgive” schizophrenia if it were a rarer disease than it is, say one in a million or one within a billion chance of developing it or if it actually contributed something to humanity, like how pathogens hold given us a strong immune system. But instead it’s a disease that just isolates the person…

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Kids and Drugs – What Parents Need to Know

As the parents of children growing up in today’s society, you may be alarmed to read about the statistics dealing with drug abuse among kids. While many of these adults are familiar with the older drugs such as marijuana and cocaine, the newer ones may be confusing. The following is a brief explanation of some of these “New Age” drugs and the symptoms to look for if your children may begin abusing them.

One of the drugs that you may have heard of is “ecstasy,” which is the street name for MDMA (methylenedioxymethamphetamine). This drug causes hallucinations and also acts as a stimulant. Used by many children much in the way that people used LSD in the sixties, the effects of using MDMA are much the same as those caused by amphetamines and cocaine. These include sleeplessness, confusion, depression, anxiety, paranoia, and drug cravings. It also causes muscle tension, profuse sweating, and an increase in blood pressure and heart rate. Usually found in a white pill form, this drug is also known as “Adam” and “XTC.” If you suspect that your child is taking “ecstasy,” you should talk to him and explain the dangers involved in using this particular drug. If a user ceases to abuse MDMA, there are no withdrawal symptoms that are known to accompany some other substances.

While many parents know what cocaine is, many do not realize that crack is also a form of this drug. Powdered cocaine is mixed with water and baking soda and heat is applied, leaving a rock of purified cocaine. This crack rock is then smoked, giving a more intense “buzz” than regular cocaine can give. Due to the activity of smoking as compare to snorting this drug, the effects of crack last for a much shorter amount of time.

The symptoms of crack use are much the same as they are for regular cocaine. These side effects include hyperactivity, increased heart rate, and higher blood pressure. Due to cocaine’s effect on the appetite, excessive use can lead to serious malnutrition and a substantial weight loss. Long term or large quantity use can lead to a heart attack, stroke, seizures, respiratory failure, and even death. As the addiction to crack is mostly psychological, there are no physical withdrawal symptoms when the user quits.

Prescription drug abuse is also becoming a growing problem among America’s youth. One such drug is oxycontin, a pill that is used as a painkiller. Also known as “hillbilly heroin,” young people tend to smash the capsules, allowing them to snort or swallow a more potent dosage of the drug than the time-released capsule will allow. The resulting “high” is compared to the buzz that people receive when doing heroin, thus the nickname. Many drug centers are reporting large numbers of cases of oxycontin addiction in young people, many of which had no legal prescription for the drug.

The symptoms of this drug include euphoria and may be accompanied by stomach and bowel problems. It can also cause respiratory problems and organ failure when used over a long period of time. When a long time user is taking off the medication, they will experience withdrawal symptoms similar to those of other addictive drugs, such as heroin. If you think that your child is abusing oxycontin, you should confront him immediately. If he experiences withdrawal symptoms, you should seek medical help as he may become very ill and disoriented.

These are just a few of the many drugs that seem to be becoming a problem with today’s youth. If you have any questions or concerns about your child’s possible drug usage, you should talk to a doctor or other health professional to make sure that you have all the information that you will need to help your child overcome his drug dependency.

Drug and Alcohol Detox at Clearview Los Angeles

Medically facilitated detoxification services are available through our Primary Residential/Inpatient Program.

Detoxification (detox) can be defined as a period of treatment where an individual is helped to overcome their physical dependence on a substance. Detox is intended to relieve the physical symptoms of withdrawal and helps prepare the patient for entry into a treatment program or rehab center. The ultimate goal of detox is to prepare the patient for long term sobriety and recovery.

Alcohol detox can cause a variety of physical symptoms and psychological ramifications. The process of alcohol detox can be traumatic and can trigger any number of side effects including tremors (the shakes), headaches, vomiting, perspiration, restlessness, loss of appetite and insomnia. More serious effects of alcohol detox can be Delirium Tremors (DT’s), autonomic hyperactivity and seizures (convulsions).

The time necessary for  alcohol detox treatment can be anywhere from 3 to 10 days. A variety of medications and procedures are used to detox a patient from alcohol.

Withdrawal from drugs is caused by stopping or dramatically reducing drug use after heavy and prolonged use. The reaction frequently includes sweating, shaking, headache, drug craving, nausea, vomiting, abdominal cramping, diarrhea, inability to sleep, confusion, agitation, depression, anxiety, and other behavioral changes.

Often, there is a significant, self induced, psychological dependence associated with these substances and therefore, a period of initial stabilization followed by residential treatment is advisable. Treatment of withdrawal (detox) includes closely monitoring the person’s vital signs, supportive care and medications. The time period for drug detox is generally 3 to 7 days.

Detox at Clearview

Clearview provides detoxification services in a safe, comfortable, home-like environment. Clients work with a medical doctor who specializes in detoxification methods.

Proper detoxification and minimization of acute and post acute withdrawal symptoms are essential to the treatment process and can greatly increase the likelihood of a client successfully completing treatment.
Clearview utilizes the latest detoxification techniques and medications depending on the patient’s pattern of abuse. When appropriate, Subutex and Suboxone are utilized for opiate detoxification. Our goal is to make the patient as comfortable as possible during the detoxification process.

Clients are rigorously monitored and receive support and guidance from our trained staff while they are detoxed. Gradually, they begin to participate in therapeutic services.

Common substances that clients are detoxed from include:
•  Alcohol
•  Cocaine
•  Heroin and other opiates such as Vicodin and Oxycotin
•  Benzodiazapines such as Xanax and Valium
•  Stimulants pills such as Aderal and Ritalin
•  Methamphetamine and speed
•  Marijuana
•  Club drugs such as Ecstasy and GHB
•  Muscle relaxers
Clearview offers everything that traditional  treatment programs for Alcoholism provide, and more. While standard education, counseling, relapse prevention, and introduction to 12-Step Programs make up the entire curriculum at most other programs, at Clearview it’s just a beginning.

Marijuana withdrawals trying to quit for good?

okay, so i have been smoking weed for 5 yrs now pretty heavily and i want to kick the habit for good now. I have tried to quit in the past, the longest i have gone without it is less then 2 months. I will quit but then smoke again because i have dreams about smoking, strong cravings, and stress. My question is has anyone else tried to quit and what are somethings to help with the cravings and withdrawals? like, should i be taking a supplement or something or any other tips
the withdrawals are more psychological then physical

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Detoxification From Addictive Substances

Detoxification (”detox”), or withdrawal, is the period of time it takes your body to adjust to being without a substance which it used to have regularly. During this time period a previous bodily “homeostasis” is restored, one based on not using the substance or substances. This restored homeostasis is similar to the one you had before you started using the substances regularly.

Homeostasis refers to the body’s maintenance, by an ongoing balancing act, of a stable internal condition. If you go scuba diving to a depth of 100 feet, your body adjusts to having that much additional weight pressing upon it. We could say that the body is pressing back as much as the weight of the water is pressing in, thereby allowing the body to maintain its internal functioning. If you come to the surface too quickly, however, your body cannot re-adjust fast enough. You get “the bends” (decompression sickness). Proper scuba diving therefore involves coming to the surface slowly enough that you do not get sick. The time taken to come to the surface corresponds to the time it takes for detoxification from addictive substances.

Detoxification can also refer to the removal of toxic substances from the body. To the extent addictive substances are toxic this definition also applies. In addiction, however, the primary meaning of detoxification is the readjustment of the body’s homeostasis.

Some classes of substances create more concern about detoxification than others. Stimulants (cocaine, methamphetamine, Ritalin, nicotine, caffeine, etc) do not need medical supervision for withdrawal. The withdrawal syndrome can be uncomfortable (much like having the flu) but is not potentially fatal. Hallucinogens and marijuana may have no withdrawal symptoms or only minor ones. Therefore, with any of these substances, one can stop use completely at any time. Tapering off is not needed. For substances not listed here it would be wise to seek medical consultation if you are using them on a daily basis. If you use a substance intermittently, with days between uses, then you already know what it feels like when you take off a few days.

The two primary classes of substances for which detoxification is a concern are depressants-as in central nervous system depressants (including alcohol, benzodiazepines such as Valium, sedatives, tranquilizers, and some sleep aids)-and opiates/opioids (including heroin, methadone, opium, Vicodin, and Suboxone). Detox takes 3 to 10 days typically, depending on the substance and your history with it, your overall health, your age, and other factors. Detox is often accomplished in a hospital ward devoted to detox only. People get medical detox for two reasons: 1) prescribed medications can make the process easier, and 2) simply going “cold turkey” (stopping your addictive substance suddenly) can make you very sick or even kill you. Therefore, even if you do not wish to have treatment for the addictive behavior itself, it is safest to seek medical attention for the detox process.

Tapering off your substance, perhaps over several weeks, is a reasonable approach from a medical perspective, but is often a poor approach in practice. If you have the ability to taper off, you might not have become physically dependent in the first place! Tapering off has more chance of working if your dependence on the drug is primarily physical not psychological. This condition might have arisen, for instance, if you were taking a pain medication for a long time, but never developed a psychological dependence on it.

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